It tells the true story of three women whose lives were affected by sexual desire. They are each a mother in her 30s who rekindled her relationship with her high school sweetheart because her husband refused physical intimacy. A 23-year-old woman reported a former teacher,The teacher accused the heroine of having sex with her when she was 17 years old, and a female restaurant owner whose husband loved to watch his wife having sex with others.

Gia, a grief-stricken writer, decides to write a book about female desire.The story centers on Lena, a housewife from Indiana, Slawn, a charismatic entrepreneur from the Northeastern United States, and Maggie, a waitress from North Dakota.

Lena escapes a stagnant marriage and a painful body; she joins Dr. Henry's women's group in an attempt to reconnect with the love of her life and begins a friendship with Gia.

An unpleasant visit from his mother prompts Sloane to get closer to Will; Richard tries to satisfy Sloan's desires in a different, doomed to fail way.

Maggie found the courage to tell her parents and police about her relationship with her high school teacher, a relationship that has shaped her life ever since.

Going back in time, Gia struggles to write a book about sex in America; starting her own love story, Gia deals with the loss of a loved one; she moves to Indiana and forms a relationship with Lena.

Lena, Sloane, and Maggie bond with each other's desires in mind, unaware of the consequences that await them.

In Indiana, Gia and Lena's friendship is threatened by Jack's sudden arrival and the revelation of long-hidden truths.

When Aaron Knodel goes to trial, Maggie is forced to come to terms with a huge loss.

Sloane hatches a secret plan to get everything she wants, culminating in a night of intimacy and revelations.

Lena, Sloan, Maggie and Gia all must make big decisions about their futures.The show is adapted from the best-selling book by Lisa Taddeo.