The story takes place in 1348, when the Black Death, the deadliest epidemic in human history, swept through the city of Florence.A handful of nobles are invited to retreat with their servants to a grand villa in the Italian countryside to wait out the plague.To pass the time, they took turns telling each other stories that ranged from witty to debauched.But as society gradually becomes disordered, a promiscuous party in the Tuscan mountains begins to evolve into a life-or-death battle for survival.
As the plague spreads through Florence, a group of self-centered nobles with secrets and ulterior motives flee to the countryside.
Filomena's arrival threatens Licisca's plans.Pampinea desperately wants to find Leonardo, while Neifile is waiting for God's help.
Pampinea becomes the mistress of the house, Neifile and Panfilo receive sad news, and love blossoms within the group.
A new guest threatens Pampinea's status.Neifile learns the truth about her husband.Filomena attempts to regain her identity.
The nobles and servants make plans to take back the villa from Ruggiero.During their exile, Licisca and Filomena tried to reconcile their differences.
Neifile and Panfilo open up to each other.Tindaro has a good relationship with Stratilia's son.Licisca and Filomena encounter a group of mercenaries.
Sirisco tries to drive Pampinea out of the villa.Licisca accepted her origins.A new heir lays claim to the villa.
The nobles and servants try to ensure their survival by striking a deal with mercenaries, who approach to break down the villa's door.