During a public surgery performed by Amagi (Ninomiya Kazuya) at the International Society of Cardiac Surgery, the patient Tokunaga (Hajime Inoue), whose thoracic artery was removed, experienced a sharp rise in body temperature and developed malignant hyperthermia.However, there are currently no drugs that can suppress malignant hyperthermia.Amagi, who overlapped with his mother's nightmare, decided to use an artificial heart and lungs during heart bypass surgery, an extremely dangerous operation, and Takato (Kotaro Koizumi) came to support him.However, all three coronary arteries used for patient Tokunaga's bypass were severed.What does that surgical mark mean?

Furthermore, Shingyoji (Koji Ishizaka) at the venue advised Amagiyama to stop the operation as a sign of the society's intention.However, Saeki (Sayo Uchino) urged the operation to continue and told Amagi the real purpose of establishing the new hospital.

At the same time, Yui (Reiho Horikoshi) of Tojo University developed acute mitral valve insufficiency.In a very dangerous state, Sera (Takeuchi Ryoma) performed emergency surgery with the help of Kurosaki (Hashimoto Satoshi).However, he encountered an unexpected accident...

Two jobs at the same time in a worst-case scenario.What is the fate of these two people!?

And, surrounding the sealed direct analysis and all the truth about mosis, the meaning of the broken Black Guards agreement is revealed!

Then the stage turned to Australia again….